Data di Pubblicazione:
1998
Citazione:
Symptoms of inherited factor V deficiency in 35 Iranian patients / M. Lak, R. Sharifian, F. Peyvandi, P.M. Mannucci. - In: BRITISH JOURNAL OF HAEMATOLOGY. - ISSN 0007-1048. - 103:4(1998), pp. 1067-1069.
Abstract:
The type of bleeding symptom has been evaluated in 35 Iranian patients with an inherited deficiency of factor V; with plasma levels between 1% and 10%. The most frequent symptoms included epistaxis and excessive bleeding after surgery. Haemarthroses and muscle haematomas were less common, even in severely deficient patients. More severe symptoms such as gastrointestinal and central nervous system bleeding were rare. The severity of bleeding symptoms was only partially related to the degree of factor V deficiency in plasma. On the whole, human factor V deficiency is characterized by a moderately severe bleeding phenotype.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Bleeding symptoms; Factor V deficiency; Inherited coagulation disorders
Elenco autori:
M. Lak, R. Sharifian, F. Peyvandi, P.M. Mannucci
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