Data di Pubblicazione:
1988
Citazione:
GnRH agonists in the treatment of endometriosis / L. Fedele, S. Bianchi, L. Arcaini, P. Vercellini, G.B. Candiani. - In: ACTA EUROPAEA FERTILITATIS. - ISSN 0587-2421. - 19:1(1988), pp. 5-12.
Abstract:
GnRH agonists, synthetic peptide analogs of GnRH, desensitize pituitary receptors for the native molecule, thus causing reversible hypogonadotropic hypogonadism. Numerous clinical studies have suggested that these compounds are efficacious in the treatment of endometriosis, but it is not clear whether they are superior to the other drugs used in treatment of this disease. The frequency of recurrence of pain symptoms at the end of treatment is high and the data on recovery of fertility are conflicting. Long-term administration of GnRH agonists is a safe and well tolerated treatment but its role in the management of endometriosis is still not well defined.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Animals ; Humans ; Pituitary Hormone-Releasing Hormones ; Clinical Trials as Topic ; Endometriosis ; Female
Elenco autori:
L. Fedele, S. Bianchi, L. Arcaini, P. Vercellini, G.B. Candiani
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