Data di Pubblicazione:
2002
Citazione:
Evaluating test-statistics to select interesting genes / C. Kooperberg, S. Sipione, L.M. LeBlanc, A.D. Strand, E. Cattaneo, J.M. Olson. - In: HUMAN MOLECULAR GENETICS. - ISSN 0964-6906. - 11:19(2002), pp. 2223-2232.
Abstract:
A randomization procedure to evaluate the significance level and the false-discovery rate in complex microarray experiments is proposed. A related graph can be used to compare different test statistics that can be used to analyze the same experiment. This graph is closely related to receiver operator characteristic (ROC) curves. The proposed method is applied to a subset of the data from a cell-line experiment related to Huntington's disease. A small simulation study compares the effectiveness of the proposed procedure with the significance analysis of microarrays (SAM) procedure.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
C. Kooperberg, S. Sipione, L.M. Leblanc, A.D. Strand, E. Cattaneo, J.M. Olson
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