Sequential stereoselective catalysis: Two single-flask reactions of a substrate in the presence of a bifunctional chiral ligand and different transition metals
Articolo
Data di Pubblicazione:
2003
Citazione:
Sequential stereoselective catalysis: Two single-flask reactions of a substrate in the presence of a bifunctional chiral ligand and different transition metals / R. Annunziata, M. Benaglia, M. Cinquini, F. Cozzi, A. Puglisi. - In: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. - ISSN 1434-193X. - :8(2003), pp. 1428-1432.
Abstract:
A new bifunctional ligand capable of promoting different stereoselective catalytic transformations in combination with different transition metals has been prepared by connecting with a spacer a bis(oxazoline) to dihydroquinidine; this ligand was employed in a one-flask procedure in which methyl (E)-3-(4-vinylphenyl)propenoate underwent first cyclopropanation at the electron-rich double bond and then dihydroxylation at the electron-poor alkene to afford a product containing four stereocenters with complete regiocontrol and high stereoselectivity. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003).
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Bifunctional ligand; Chiral ligands; Cyclopropanation; Dihydroxylation; Stereoselective catalysis
Elenco autori:
R. Annunziata, M. Benaglia, M. Cinquini, F. Cozzi, A. Puglisi
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