Data di Pubblicazione:
2004
Citazione:
Contrast enhanced CT and PET in lung cancer screening / M. Bellomi, E. De Fiori, S. Ferretti, C. Rampinelli, C. Trentin. - In: CANCER IMAGING. - ISSN 1740-5025. - (2004). [10.1102/1470-7330.2004.0033]
Abstract:
This paper aims to discuss the role and the accuracy of positron emission tomography (PET) and to evaluate computed
tomography (CT) contrast enhancement in diagnosing the nature of lung nodules detected by low-dose CT, performed
as screening for lung cancer. When applying strict admission criteria to the test, CT contrast enhancement is feasible
in 40% of nodules and gives an accurate diagnosis of benignity when enhancement is <15 HU: this occurs in only 5%
of cases, but the diagnosis has to be considered certain, sparing further examination and/or follow-up. PET, performed
with the most up-to-date equipment, can evaluate nodules with diameter >7 mm. The sensitivity is 87% and specificity
76%. Contrast enhancement study and PET are promising in the diagnostic work-up of lung nodules, as they reduce
follow-up, the number of Fine Needle Aspiration Biopsy (FNAB), costs, radiation exposure and patients’ anxiety.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Diagnostic imaging; lung cancer (diagnosis); computed tomography; X-rays; contrast medium; positron emission
tomography.
Elenco autori:
M. Bellomi, E. De Fiori, S. Ferretti, C. Rampinelli, C. Trentin
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