Late onset of hepatitis B virusreactivation following hematopoietic stem cell transplantation : successfultreatment with combined entecavir plus tenofovir therapy
Articolo
Data di Pubblicazione:
2012
Citazione:
Late onset of hepatitis B virusreactivation following hematopoietic stem cell transplantation : successfultreatment with combined entecavir plus tenofovir therapy / L. Milazzo, M. Corbellino, A. Foschi, V. Micheli, A. Dodero, A. Mazzocchi ,V. Montefusco, G. Zehender, S. Antinori. - In: TRANSPLANT INFECTIOUS DISEASE. - ISSN 1398-2273. - 14:1(2012 Feb), pp. 95-98. [10.1111/j.1399-3062.2011.00659.x]
Abstract:
Prophylaxis with lamivudine (LAM) is recommended for
hepatitis B core antibody-positive allogenic hematopoietic stem cell
transplant (HSCT) recipients, but the optimal timing for the institution
and duration of the prophylaxis is still unknown. Furthermore,
considering the high rate of mortality associated with hepatitis B virus
reactivation (HBV-R), the most potent and long-term e¡ective antiviral
regimen should be considered.We report here a case of late onset of
HBV-R after a long-term prophylaxis with LAM in a patient who
underwent HSCT for non-Hodgkin lymphoma and who was
successfully treated with a combination antiviral regimen including
entecavir and tenofovir disoproxil fumarate
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
hepatitis B virus ; HBV reactivation ; tenofovir ; entecavir ; allogeneic hematopoietic stem cell transplant
Elenco autori:
L. Milazzo, M. Corbellino, A. Foschi, V. Micheli, A. Dodero, A. Mazzocchi, V. Montefusco, G. Zehender, S. Antinori
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