Global versus local linear beat-to-beat analysis of the relationship between arterial pressure and pulse transit time during dynamic exercise
Articolo
Data di Pubblicazione:
2006
Citazione:
Global versus local linear beat-to-beat analysis of the relationship between arterial pressure and pulse transit time during dynamic exercise / A. Porta, C. Gasperi, G. Nollo, D. Lucini, P. Pizzinelli, R. Antolini, M. Pagani. - In: MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING. - ISSN 0140-0118. - 44:4(2006), pp. 331-337. [10.1007/s11517-006-0042-4]
Abstract:
Global linear analysis has been traditionally performed to verify the relationship between pulse transit time (PTT) and systolic arterial pressure (SAP) at the level of their spontaneous beat-to-beat variabilities: PTT and SAP have been plotted in the plane (PTT,SAP) and a significant linear correlation has been found. However, this relationship is weak and in specific individuals cannot be found. This result prevents the utilization of the SAP-PTT relationship to derive arterial pressure changes from PTT measures on an individual basis. We propose a local linear approach to study the SAP-PTT relationship. This approach is based on the definition of short SAP-PTT sequences characterized by SAP increase (decrease) and PTT decrease (increase) and on their search in the SAP and PTT beat-to-beat series. This local approach was applied to PTT and SAP series derived from 13 healthy humans during incremental supine dynamic exercise (at 10, 20 and 30% of the nominal individual maximum effort) and compared to the global approach. While global approach failed in some subjects, local analysis allowed the extraction of the gain of the SAP-PTT relationship in all subjects both at rest and during exercise. When both local and global analyses were successful, the local SAP-PTT gain is more negative than the global one as a likely result of noise reduction.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Arterial pressure; Cardiovascular variability; Dynamic exercise; Pulse transit time
Elenco autori:
A. Porta, C. Gasperi, G. Nollo, D. Lucini, P. Pizzinelli, R. Antolini, M. Pagani
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