The contribution of occupational exposure vs. cigarette smoking in determining the internal dose of 1,3-butadiene in Italian workers
Altro
Data di Pubblicazione:
2004
Citazione:
The contribution of occupational exposure vs. cigarette smoking in determining the internal dose of 1,3-butadiene in Italian workers / S. Fustinoni, L. Perbellini, L. Campo, L. Scibetta, V. Foà. ((Intervento presentato al 6. convegno International Symposium on Biological Monitoring in Occupational and Environmental Health tenutosi a Heidelberg (Germania) nel 2004.
Abstract:
Aims: The aim of this study was to compare the contribution of occupational exposure and smoking habit in determining the total intake of 1,3-butadiene (BD), a probable carcinogen to humans, in chemical workers.
Methods: Forty-two BD healthy male petrochemical workers (W), and forty-three internal controls (C) entered the study. Personal exposure to airborne BD was evaluated as time weighted average value during the work-shift. BD in exhaled air, blood and urine was measured in specimens collected both at the beginning and at the end of the work-shift. Information on cigarette smoking was obtained by questionnaire.
Results: Median exposure to BD was 1.5 (ranging from <0.1-201 ) µg/m3 in W, and 0.4 (<0.1-10) µg/m3 in C. BD in exhaled air, blood and urine was about 1.5-3 times higher in W then in C (p<0.05). Correlations between these biomarkers and airborne BD (0.28
Tipologia IRIS:
14 - Intervento a convegno non pubblicato
Elenco autori:
S. Fustinoni, L. Perbellini, L. Campo, L. Scibetta, V. Foà
Link alla scheda completa: